Big science leads to BigNeuron
However, with the latest advances in neuronal labeling, high-resolution imaging and computer power increase, at least semi-automated procedures become better and better. In this Nature Methods paper, we provided some “ground truth” reconstructions done by Alvar Prönneke at that time, which was used to benchmark software mainly developed by Hanchuan Peng’s lab.
If you want to learn more, please check out