Seibertz F, Rapedius M, Fakuade FE, Tomsits P, Liutkute A, Cyganek L, Becker N, Majumder R, Clauß S, Fertig N, Voigt N.A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes. Commun Biol. 2022; 5(1):969. doi: 10.1038/s42003-022-03871-2
Lyra-Leite DM, Gutiérrez-Gutiérrez Ó, Wang M, Zhou Y, Cyganek L, Burridge PW. A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming. STAR Protoc. 2022; 3(3):101560. doi: 10.1016/j.xpro.2022.101560
Fan X, Cyganek L, Nitschke K, Uhlig S, Nuhn P, Bieback K, Duerschmied D, El-Battrawy I, Zhou X, Akin I.Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Int J Mol Sci. 2022; 23(15):8507. doi: 10.3390/ijms23158507
Zhong R, Schimanski T, Zhang F, Lan H, Hohn A, Xu Q, Huang M, Liao Z, Qiao L, Yang Z, Li Y, Zhao Z, Li X, Rose L, Albers S, Maywald L, Müller J, Dinkel H, Saguner A, Janssen JWG, Swamy N, Xi Y, Lang S, Kleinsorge M, Duru F, Zhou X, Diecke S, Cyganek L, Akin I, El-Battrawy I.A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. Int J Mol Sci. 2022; 23(15):8313. doi: 10.3390/ijms23158313
Zhong R, Zhang F, Yang Z, Li Y, Xu Q, Lan H, Cyganek L, El-Battrawy I, Zhou X, Akin I, Borggrefe M.Epigenetic mechanism of L-type calcium channel β-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation. Europace. 2022; euac091. doi: 10.1093/europace/euac091
Jakobi T, Groß J, Cyganek L, Doroudgar S.Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. Front Cardiovasc Med. 2022; 9:844441. doi: 10.3389/fcvm.2022.844441
Xu Q, Huang X, Meng Z, Li Y, Zhong R, Li X, Cyganek L, El-Battrawy I, Akin I, Zhou X, Lan H.Antiarrhythmic Effects of Vernakalant in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Short QT Syndrome Type 1. J Cardiovasc Dev Dis. 2022; 9(4):112. doi: 10.3390/jcdd9040112
Kontaridis MI, Roberts AE, Schill L, Schoyer L, Stronach B, Andelfinger G, Aoki Y, Axelrad ME, Bakker A, Bennett AM, Broniscer A, Castel P, Chang CA, Cyganek L, Das TK, den Hertog J, Galperin E, Garg S, Gelb BD, Gordon K, Green T, Gripp KW, Itkin M, Kiuru M, Korf BR, Livingstone JR, López-Juárez A, Magoulas PL, Mansour S, Milner T, Parker E, Pierpont EI, Plouffe K, Rauen KA, Shankar SP, Smith SB, Stevenson DA, Tartaglia M, Van R, Wagner ME, Ware SM, Zenker M. The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery. Am J Med Genet A. 2022; 188(6):1915-1927. doi: 10.1002/ajmg.a.62716
Zhong R, Zhang F, Yang Z, Li Y, Xu Q, Lan H, Lang S, Cyganek L, Burgermeister E, El-Battrawy I, Zhou X, Akin I, Borggrefe M.Regulation of Ion Channel Function in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Cancer Cell Secretion Through DNA Methylation. Front Cardiovasc Med. 2022; 9:839104. doi: 10.3389/fcvm.2022.839104
Li W, Luo X, Poetsch MS, Oertel R, Nichani K, Schneider M, Strano A, Hasse M, Steiner RP, Cyganek L, Hettwer K, Uhlig S, Simon K, Guan K, Schubert M. Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Pharmaceuticals. 2022; 15(2):220. doi: 10.3390/ph15020220
Huang M, Yang Z, Li Y, Lan H, Cyganek L, Yuecel G, Lang S, Bieback K, El-Battrawy I, Zhou X, Borggrefe M, Akin I.Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy. Front Cardiovasc Med. 2022; 8:777463. doi: 10.3389/fcvm.2021.777463
Gönenc II, Wolff A, Schmidt J, Zibat A, Müller C, Cyganek L, Argyriou L, Räschle M, Yigit G, Wollnik B.Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures. Hum Mol Genet. 2022; 31(13):2185-2193. doi: 10.1093/hmg/ddab373
Pavez-Giani MG, Cyganek L. Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells. Front Cell Dev Biol. 2022; 9:800529. doi: 10.3389/fcell.2021.800529
Lutter G, Puehler T, Cyganek L, Seiler J, Rogler A, Herberth T, Knueppel P, Gorb SN, Sathananthan J, Sellers S, Müller OJ, Frank D, Haben I. Biodegradable Poly-ε-Caprolactone Scaffolds with ECFCs and iMSCs for Tissue-Engineered Heart Valves. Int J Mol Sci. 2022; 23(1):527. doi: 10.3390/ijms23010527
2021
El-Battrawy I, Lan H, Cyganek L, Maywald L, Zhong R, Zhang F, Xu Q, Lee J, Duperrex E, Hierlemann A, Saguner AM, Duru F, Kovacs B, Huang M, Liao Z, Albers S, Müller J, Dinkel H, Rose L, Hohn A, Yang Z, Qiao L, Li Y, Lang S, Kleinsorge M, Mügge A, Aweimer A, Fan X, Diecke S, Akin I, Li G, Zhou X. Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening. Clin Transl Med. 2021; 11(12):e646. doi: 10.1002/ctm2.646
Barbarics B, Eildermann K, Kaderali L, Cyganek L, Plessmann U, Bodemeyer J, Paul T, Ströbel P, Urlaub H, Tirilomis T, Lenz C, Bohnenberger H. Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis. Sci Rep. 2021; 11(1):24389. doi: 10.1038/s41598-021-03907-3
Fomin A, Gärtner A, Cyganek L, Tiburcy M, Tuleta I, Wellers L, Folsche L, Hobbach AJ, von Frieling-Salewsky M, Unger A, Hucke A, Koser F, Kassner A, Sielemann K, Streckfuß-Bömeke K, Hasenfuss G, Goedel A, Laugwitz KL, Moretti A, Gummert JF, Dos Remedios CG, Reinecke H, Knöll R, van Heesch S, Hubner N, Zimmermann WH, Milting H, Linke WA. Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations. Sci Transl Med. 2021; 13(618):eabd3079. doi: 10.1126/scitranslmed.abd3079
Kusch H, Kossen R, Suhr M, Freckmann L, Weber L, Henke C, Lehmann C, Rheinländer S, Aschenbrandt G, Kühlborn LK, Marzec B, Menzel J, Schwappach B, Zelarayán LC, Cyganek L, Antonios G, Kohl T, Lehnart SE, Zoremba M, Sax U, Nussbeck SY. Management of Metadata Types in Basic Cardiological Research. Stud Health Technol Inform. 2021; 283:59-68. doi: 10.3233/SHTI210542
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC. Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation. Stem Cell Res. 2021; 56:102518. doi: 10.1016/j.scr.2021.102518
Schoger E, Zimmermann WH, Cyganek L, Zelarayán LC. Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression. Stem Cell Res. 2021; 55:102473. doi: 10.1016/j.scr.2021.102473
Sattler K, El-Battrawy I, Cyganek L, Lang S, Lan H, Li X, Zhao Z, Utikal J, Wieland T, Borggrefe M, Zhou X, Akin I. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes. Sci Rep. 2021; 11(1):14689. doi: 10.1038/s41598-021-93958-3
Huang M, Liao Z, Li X, Yang Z, Fan X, Li Y, Zhao Z, Lang S, Cyganek L, Zhou X, Akin I, Borggrefe M, El-Battrawy I. Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1. Front Pharmacol. 2021; 12:675003. doi: 10.3389/fphar.2021.675003
Rössler U, Hennig AF, Stelzer N, Bose S, Kopp J, Søe K, Cyganek L, Zifarelli G, Ali S, von der Hagen M, Strässler E, Hahn G, Pusch M, Stauber T, Izsvák Z, Gossen M, Stachelscheid H, Kornak U. Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis. J Bone Miner Res. 2021; ahead of print. doi: 10.1002/jbmr.4322
Huang M, Fan X, Yang Z, Cyganek L, Li X, Yuecel G, Lan H, Li Y, Wendel A, Lang S, Bieback K, El-Battrawy I, Zhou X, Akin I, Borggrefe M. Alpha 1-adrenoceptor signalling contributes to toxic effects of catecholamine on electrical properties in cardiomyocytes. Europace. 2021; 23(7):1137-1148. doi: 10.1093/europace/euab008
Yousefi R, Fornasiero EF, Cyganek L, Montoya J, Jakobs S, Rizzoli SO, Rehling P, Pacheu-Grau D. Monitoring mitochondrial translation in living cells. EMBO Rep. 2021; e51635. doi: 10.15252/embr.202051635
Li W, Stauske M, Luo X, Wagner S, Vollrath M, Mehnert CS, Schubert M, Cyganek L, Chen S, Hasheminasab SM, Wulf G, El-Armouche A, Maier LS, Hasenfuss G, Guan K. Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation. Front Cell Dev Biol. 2020; 8:592893. doi: 10.3389/fcell.2020.592893 Lan H, Xu Q, El-Battrawy I, Zhong R, Li X, Lang S, Cyganek L, Borggrefe M, Zhou X, Akin I. Ionic Mechanisms of Disopyramide Prolonging Action Potential Duration in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1. Front Pharmacol. 2020; 11:554422. doi: 10.3389/fphar.2020.554422
Schoger E, Argyriou L, Zimmermann WH, Cyganek L, Zelarayán LC. Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation. Stem Cell Res. 2020; 48:101944. doi: 10.1016/j.scr.2020.101944
Luo X, Li W, Künzel K, Henze S, Cyganek L, Strano A, Poetsch MS, Schubert M, Guan K. IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency. Front Cell Dev Biol. 2020; 8. doi: 10.3389/fcell.2020.00772
Hanses U, Kleinsorge M, Roos L, Yigit G, Li Y, Barbarics B, El-Battrawy I, Lan H, Tiburcy M, Hindmarsh R, Lenz C, Salinas G, Diecke S, Müller C, Adham I, Altmüller J, Nürnberg P, Paul T, Zimmermann WH, Hasenfuss G, Wollnik B, Cyganek L. Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated Cardiomyopathy. Circulation. 2020. doi: 10.1161/CIRCULATIONAHA.119.044794
Grunert M, Appelt S, Schönhals S, Mika K, Cui H, Cooper A, Cyganek L, Guan K, Sperling SR. Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation. Sci Rep. 2020; 10(1):10921. doi: 10.1038/s41598-020-67872-z
Ganapathi M, Argyriou L, Martínez-Azorín F, Morlot S, Yigit G, Lee TM, Auber B, von Gise A, Petrey DS, Thiele H, Cyganek L, Sabater-Molina M, Ahimaz P, Cabezas-Herrera J, Sorlí-García M, Zibat A, Siegelin MD, Burfeind P, Buchovecky CM, Hasenfuss G, Honig B, Li Y, Iglesias AD, Wollnik B. Bi-allelic missensedisease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis. Hum Genet. 2020. doi: 10.1007/s00439-020-02188-6
Tiburcy M, Meyer T, Liaw NY, Zimmermann WH. Generation of Engineered Human Myocardium in a Multi-well Format. STAR Protocols. 2020; 100032. doi: 10.1016/j.xpro.2020.100032 > Download now
Kleinsorge M, Cyganek L. Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes. STAR Protocols. 2020; 100026. doi: 10.1016/j.xpro.2020.100026 > Download now
Beuthner BEC, Topci R, Derks M, Franke T, Seelke S, Puls M, Schuster A, Toischer K, Valentova M, Cyganek L, Zeisberg EM, Jacobshagen C, Hasenfuss G, Nussbeck SY. Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement. Open J Bioresour. 2020; 7:3. doi: 10.5334/ojb.65
Khadjeh S, Hindmarsh V, Weber F, Cyganek L, Vidal RO, Torkieh S, Streckfuss-Bömeke K, Lbik D, Tiburcy M, Mohamed BA, Bonn S, Toischer K, Hasenfuss G. CRISPLD1: a novel conserved target in the transition to human heart failure. Basic Res Cardiol. 2020; 115(3):27. doi: 10.1007/s00395-020-0784-4
Buljubasic F, El-Battrawy I, Lan H, Lomada SK, Chatterjee A, Zhao Z, Li X, Zhong R, Xu Q, Huang M, Liao Z, Lang S, Cyganek L, Zhou X, Wieland T, Borggrefe M, Akin I. Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy. J Clin Med. 2020; 9(2). doi: 10.3390/jcm9020486
2019
El-Battrawy I, Müller J, Zhao Z, Cyganek L, Zhong R, Zhang F, Kleinsorge M, Lan H, Li X, Xu Q, Huang M, Liao Z, Moscu-Gregor A, Albers S, Dinkel H, Lang S, Diecke S, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou X, Akin I. Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Front Cell Dev Biol. 2019; 7:261. doi: 10.3389/fcell.2019.00261
El-Battrawy I, Albers S, Cyganek L, Zhao Z, Lan H, Li X, Xu Q, Kleinsorge M, Huang M, Liao Z, Zhong R, Rudic B, Müller J, Dinkel H, Lang S, Diecke S, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou X, Akin I. A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes. Europace. 2019; 21(9):1410-1421. doi: 10.1093/europace/euz122
Sattler K, El-Battrawy I, Zhao Z, Schrottenberg C, Yücel G, Lan H, Li X, Lang S, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Ravens U, Bieback K, Borggrefe M, Zhou X, Akin I. Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes. Sci Rep. 2019; 9(1):5651. doi: 10.1038/s41598-019-42079-z
Zhao Z, Li X, El-Battrawy I, Lan H, Zhong R, Xu Q, Huang M, Liao Z, Lang S, Zimmermann WH, Cyganek L, Wieland T, Akin I, Zhou XB, Borggrefe M. Drug Testing in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1. Clin Pharmacol Ther. 2019; 106(3):642-651. doi: 10.1002/cpt.1449
2018
Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J. Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia. Cell Rep. 2018; 25(3):561-570.e6. doi: 10.1016/j.celrep.2018.09.057
Cyganek L, Tiburcy M, Sekeres K, Gerstenberg K, Bohnenberger H, Lenz C, Henze S, Stauske M, Salinas G, Zimmermann WH, Hasenfuss G, Guan K. Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight. 2018; 3(12). pii: 99941. doi: 10.1172/jci.insight.99941
El-Battrawy I, Lan H, Cyganek L, Zhao Z, Li X, Buljubasic F, Lang S, Yücel G, Sattler K, Zimmermann WH, Utikal J, Wieland T, Ravens U, Borggrefe M, Zhou XB, Akin I. Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. J Am Heart Assoc. 2018; 7(7). pii: e007394. doi: 10.1161/JAHA.117.007394
El-Battrawy I, Zhao Z, Lan H, Cyganek L, Tombers C, Li X, Buljubasic F, Lang S, Tiburcy M, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou XB, Akin I. Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy. Europace. 2018. doi: 10.1093/europace/euy042
El-Battrawy I, Zhao Z, Lan H, Li X, Yücel G, Lang S, Sattler K, Schünemann JD, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Bieback K, Bauer R, Ratte A, Pribe-Wolferts R, Rapti K, Nowak D, Wittig J, Thomas D, Most P, Katus HA, Ravens U, Schmidt C, Borggrefe M, Zhou XB, Müller OJ, Akin I. Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy. Circ Genom Precis Med. 2018; 11(3):e001893. doi: 10.1161/CIRCGEN.117.001893
Zhao Z, Lan H, El-Battrawy I, Li X, Buljubasic F, Sattler K, Yücel G, Lang S, Tiburcy M, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Borggrefe M, Zhou XB, Akin I. Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells Int. 2018; 2018:6067096. doi: 10.1155/2018/6067096
El-Battrawy I, Zhao Z, Lan H, Schünemann JD, Sattler K, Buljubasic F, Patocskai B, Li X, Yücel G, Lang S, Nowak D, Cyganek L, Bieback K, Utikal J, Zimmermann WH, Ravens U, Wieland T, Borggrefe M, Zhou XB, Akin I. Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes. Int J Cardiol. 2018; 254:195-202. doi: 10.1016/j.ijcard.2017.11.007
2017
Castillo-Gómez E, Oliveira B, Tapken D, Bertrand S, Klein-Schmidt C, Pan H, Zafeiriou P, Steiner J, Jurek B, Trippe R, Prüss H, Zimmermann WH, Bertrand D, Ehrenreich H, Hollmann M. All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class. Mol Psychiatry. 2017; 22(12):1776-1784. doi: 10.1038/mp.2016.125
Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, Raaz U, Nikolaev VO, Guan K, Thiele H, Meder B, Wollnik B, Zimmermann WH, Lüscher TF, Hasenfuss G, Templin C, Streckfuss-Bömeke K. Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy. J Am Coll Cardiol. 2017; 70(8):975-991. doi: 10.1016/j.jacc.2017.06.061
Tiburcy M, Hudson JE, Balfanz P, Schlick S, Meyer T, Chang Liao ML, Levent E, Raad F, Zeidler S, Wingender E, Riegler J, Wang M, Gold JD, Kehat I, Wettwer E, Ravens U, Dierickx P, van Laake LW, Goumans MJ, Khadjeh S, Toischer K, Hasenfuss G, Couture LA, Unger A, Linke WA, Araki T, Neel B, Keller G, Gepstein L, Wu JC, Zimmermann WH. Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair. Circulation. 2017; 135(19):1832-1847. doi: 10.1161/CIRCULATIONAHA.116.024145
Yücel G, Zhao Z, El-Battrawy I, Lan H, Lang S, Li X, Buljubasic F, Zimmermann WH, Cyganek L, Utikal J, Ravens U, Wieland T, Borggrefe M, Zhou XB, Akin I. Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes. Sci Rep. 2017; 7(1):2935. doi: 10.1038/s41598-017-03147-4
Chowdhury SK, Liu W, Zi M, Li Y, Wang S, Tsui H, Prehar S, Castro S, Zhang H, Ji Y, Zhang X, Xiao R, Zhang R, Lei M, Cyganek L, Guan K, Millar CB, Liao X, Jain MK, Boyett MR, Cartwright EJ, Shiels HA, Wang X. Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention. Circulation. 2017; 135(7):683-699. doi: 10.1161/CIRCULATIONAHA.116.022941
2016
Veerman CC, Mengarelli I, Guan K, Stauske M, Barc J, Tan HL, Wilde AA, Verkerk AO, Bezzina CR. hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities. Sci Rep. 2016; 6:30967. doi: 10.1038/srep30967
Dudek J, Cheng IF, Chowdhury A, Wozny K, Balleininger M, Reinhold R, Grunau S, Callegari S, Toischer K, Wanders RJ, Hasenfuß G, Brügger B, Guan K, Rehling P. Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome. EMBO Mol Med. 2016; 8(2):139-54. doi: 10.15252/emmm.201505644
2015
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, Stadler H, Kawabe H, Zimmermann WH, Nave KA, Schulz-Schaeffer W, Jahn O, Ehrenreich H. Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury. Mol Med. 2015; 21(1):803-815. doi: 10.2119/molmed.2015.00192
Streckfuss-Bömeke K, Cyganek L. Patientenspezifische iPS-Zellen und deren Anwendung in der Herzforschung. Biospektrum. 2015; 21(4):406-410. doi: 10.1007/s12268-015-0595-6
Kruse V, Hamann C, Monecke S, Cyganek L, Elsner L, Hübscher D, Walter L, Streckfuss-Bömeke K, Guan K, Dressel R. Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. PLoS One. 2015; 10(5):e0125544. doi: 10.1371/journal.pone.0125544
