Lost and found in the cortical microcircuit

Felix could have got lost in the jungle of “disinhibitory connections” that keep getting found in more expectable and unexpectable places. Progressing from intralaminar to translaminar circuitry, he could show that our favorite “pet” (the VIP neurons) are a reliable source of inhibiting somatostatin interneurons, not only within their home layers but also across layers. A feature that isn’t shared by parvalbumin interneurons as presynaptic cells. Interested in the details? Please check out
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP288309
Congratulations Felix!